M4255

3-Methoxy-L-tyrosine monohydrate

powder

• Synonym(s): 4-Hydroxy-3-methoxy-L-phenylalanine, L-3-O-Methyl-DOPA
• Empirical Formula (Hill Notation): C₁₀H₁₃NO₄ H₂O
• CAS Number: 200630-46-2
• Molecular Weight: 229.23
• MDL number: MFCD00150495
• UNSPSC Code: 12352209
• PubChem Substance ID: 24896916
• NACRES: NA.26

Properties

• Assay: ≥98% (HPLC)
• Quality Level: 100
• form: powder
• application(s): detection
• storage temp.: 2-8°C
• SMILES string: COc1cc(C[C@H](N)C(O)=O)ccc1O
• InChI: 1S/C10H13NO4/c1-15-9-5-6(2-3-8(9)12)4-7(11)10(13)14/h2-3,5,7,12H,4,11H2,1H3,(H,13,14)/t7-/m0/s1
• InChI key: PFDUUKDQEHURQC-ZETCQYMHSA-N

Description

Biochem/physiol Actions

3-Methoxy-L-tyrosine is a metabolite of L-Dopa.

The major metabolite of L-DOPA via catechol O-methyltransferase (COMT). 3-methoxy-L-tyrosine is neither a substrate for nor an inhibitor of L-amino acid decarboxylase activity. Inhibition of COMT enhances the anti-Parkinson activity of L-DOPA.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves