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Key Documents

H0790

Sigma-Aldrich

HIV Protease Fluorescent Substrate

Ex: 320nm, Em: 420nm

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About This Item

Empirical Formula (Hill Notation):
C50H76N14O14
Molecular Weight:
1097.22
UNSPSC Code:
12352204
NACRES:
NA.32

Quality Level

Assay

≥95% (HPLC)

form

lyophilized powder

solubility

acetonitrile: water (1:4): 1 mg/mL

storage temp.

−20°C

Amino Acid Sequence

Abz-Ala-Arg-Val-Nle-Tyr(NO2)-Glu-Ala-Nle-NH2

Biochem/physiol Actions

Substrate for HIV protease (Wildtype and mutants)

Other Notes

Substrate is cleaved between the Nle and Tyr residue, producing a fluorescence that is measured with Ex: 320nm Em: 420nm. This substrate is recognized by both the Wild Type and Drug Resistant Mutants.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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