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About This Item
Linear Formula:
H2NCH2CO2Na · xH2O
CAS Number:
Molecular Weight:
97.05 (anhydrous basis)
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.77
Recommended Products
biological source
synthetic (organic)
Quality Level
Assay
≥99% (HPLC)
form
powder
mol wt
97.05 g/mol (anhydrous basis)
technique(s)
electrophoresis: suitable
mp
197-201 °C (lit.)
SMILES string
[Na+].[H]O[H].NCC([O-])=O
InChI
1S/C2H5NO2.Na.H2O/c3-1-2(4)5;;/h1,3H2,(H,4,5);;1H2/q;+1;/p-1
InChI key
CIJQGPVMMRXSQW-UHFFFAOYSA-M
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General description
Research area: Neuroscience
Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.
Glycine is a simple non-essential amino acidIt is synthesized from choline, threonine and serine. It serves as a precursor for porphyrins, purines, glutathione and creatine.
Application
Glycine sodium salt hydrate has been used as a component of buffer for homogenization of whole muscle for protein extraction and in electrophoresis buffer. It has also been used as a neurotransmitter in immunohistochemical staining of Zebrafish spinal cord sections.
Biochem/physiol Actions
Glycine serves as a neurotransmitter in the central nervous system. It aids in increasing the quality of sleep and neurological functions. It is essential for the regulation immune function, metabolism, growth and development. Glycine modulates intracellular Ca2+ levels and cytokines production. Studies have shown that glycine treatment effectively prevents organ transplantation failure by mitigating ischemia reperfusion injury caused by cold ischemic storage. Additionally, glycine treatment also enhances graft function during transplantation. A reduction in glycine levels is observed in obesity, type 2 diabetes (T2DM), and non-alcoholic fatty liver disease (NAFLDs). Glycine is degraded to serine by glycine serine hydroxymethyltransferase 1 in cytoplasm.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Transmitters mediating 'fast' synaptic processes in the vertebrate central nervous system are commonly placed in two separate categories that are believed to exhibit no interaction at the receptor level. The 'inhibitory transmitters' (such as glycine and GABA) are considered to
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