Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

34442

Sigma-Aldrich

Acetonitrile

≥99.9% (GC), suitable for cDNA synthesis, DNA synthesis

Synonym(s):

ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
CH3CN
CAS Number:
75-05-8
Molecular Weight:
41.05
Beilstein:
741857
EC Number:
200-835-2
MDL number:
MFCD00001878
UNSPSC Code:
12191502
eCl@ss:
39031501
PubChem Substance ID:
329754743
NACRES:
NA.03

product name

Acetonitrile, suitable for DNA synthesis, ≥99.9% (GC)

vapor density

1.41 (vs air)

vapor pressure

72.8 mmHg ( 20 °C)

Assay

≥99.9% (GC)

form

liquid

autoignition temp.

973 °F

expl. lim.

16 %

technique(s)

DNA synthesis: suitable
cDNA synthesis: suitable

impurities

≤0.0001% free alkali (as NH3)
≤0.001% free acid (as CH3COOH)
≤0.001% water (Karl Fischer)

refractive index

n20/D 1.344 (lit.)

bp

81-82 °C (lit.)

mp

−45 °C (lit.)

density

0.786 g/mL at 25 °C (lit.)

format

neat

SMILES string

CC#N

InChI

1S/C2H3N/c1-2-3/h1H3

InChI key

WEVYAHXRMPXWCK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application


  • Modified QuEChERS method combined with ultra-performance liquid chromatography-tandem mass spectrometry: This research utilizes acetonitrile′s excellent solvent properties for the detection of cyclopiazonic acid in feeds. The method enhances the efficiency and accuracy of chemical analyses in food safety, demonstrating acetonitrile′s pivotal role in ensuring the quality of agricultural products (Peng et al., 2024).

  • Liquid Chromatographic Enantioseparation of Newly Synthesized Fluorinated Tryptophan Analogs: Highlighting its use in pharmaceutical research, acetonitrile is employed in the chromatographic enantioseparation of complex amino acids, essential for drug development and molecular pharmacology studies (Tanács et al., 2024).

  • Synthesis and Application of 1,8-Naphthalimide Derivatives Fluorescent Probe: Acetonitrile′s versatility is showcased in the synthesis of fluorescent probes for environmental monitoring. Its application in detecting and measuring environmental pollutants highlights its significant impact on ecological research and safety (Negi et al., 2024).

Other Notes

The article number 34442-4X2.5L will be discontinued. Please order the single bottle 34442-2.5L which is physically identical with the same exact specifications.

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2.0 °C - closed cup

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Customers Also Viewed

Slide 1 of 3

1 of 3

Acetonitrile for gas chromatography ECD and FID SupraSolv®

Supelco

1.00017

Acetonitrile

Acetonitrile suitable for HPLC, gradient grade, ≥99.9%

Sigma-Aldrich

439134

Acetonitrile

Acetonitrile HPLC Plus, ≥99.9%

Sigma-Aldrich

34998

Acetonitrile

Timo Glatter et al.
Molecular systems biology, 5, 237-237 (2009-01-22)
Protein complexes represent major functional units for the execution of biological processes. Systematic affinity purification coupled with mass spectrometry (AP-MS) yielded a wealth of information on the compendium of protein complexes expressed in Saccharomyces cerevisiae. However, global AP-MS analysis of
Elke H J Krekels et al.
Clinical pharmacokinetics, 53(6), 553-563 (2014-02-06)
From a previously validated paediatric population pharmacokinetic model, it was derived that non-linear morphine maintenance doses of 5 μg/kg(1.5)/h, with a 50 % dose reduction in neonates with a postnatal age (PNA) <10 days, yield similar morphine and metabolite concentrations
N Sorvillo et al.
Journal of thrombosis and haemostasis : JTH, 12(5), 670-679 (2014-07-01)
Acquired deficiency of ADAMTS13 causes a rare and life-threatening disorder called thrombotic thrombocytopenic purpura (TTP). Several studies have shown that aberrant glycosylation can play an important role in the pathogenesis of autoimmune diseases.N-linked glycosylation and putative O-fucosylation sites have been
Divya Subramonian et al.
Journal of proteome research, 13(9), 3905-3918 (2014-07-30)
SUMOylation is an essential posttranslational modification and regulates many cellular processes. Dysregulation of SUMOylation plays a critical role in metastasis, yet how its perturbation affects this lethal process of cancer is not well understood. We found that SUMO-2/3 modification is
Changting Xiao et al.
Diabetes, 63(7), 2394-2401 (2014-03-04)
The dipeptidyl peptidase-4 inhibitor sitagliptin, an antidiabetic agent, which lowers blood glucose levels, also reduces postprandial lipid excursion after a mixed meal. The underlying mechanism of this effect, however, is not clear. This study examined the production and clearance of
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service