66681

4,4′-Methylene-bis(2-chloroaniline)

analytical standard

• Synonym(s): 2,2′-Dichloro-4,4′-methylenedianiline, 4,4′-Diamino-3,3′-dichlorodiphenylmethane
• Linear Formula: CH₂[C₆H₃(Cl)NH₂]₂
• CAS Number: 101-14-4
• Molecular Weight: 267.15
• Beilstein: 1882318
• EC Number: 202-918-9
• MDL number: MFCD00047829
• UNSPSC Code: 41116107
• PubChem Substance ID: 329760302
• NACRES: NA.24

Properties

• grade: analytical standard
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• bp: 202-214 °C/0.3 mmHg (lit.)
• mp: 102-107 °C (lit.)
• application(s): environmental
• format: neat
• SMILES string: Nc1ccc(Cc2ccc(N)c(Cl)c2)cc1Cl
• InChI: 1S/C13H12Cl2N2/c14-10-6-8(1-3-12(10)16)5-9-2-4-13(17)11(15)7-9/h1-4,6-7H,5,16-17H2
• InChI key: IBOFVQJTBBUKMU-UHFFFAOYSA-N

Description

General description

4,4′-Methylene-bis(2-chloroaniline) is an azo dye metabolite that is deemed toxic to the environment.

Application

4,4′-Methylene-bis(2-chloroaniline) may be used as an analytical reference standard for the determination of 4,4′-methylene-bis(2-chloroaniline) in:

• Urine samples by high performance liquid chromatography (HPLC).
• Textile samples by HPLC coupled to tandem mass spectrometry (MS/MS) equipped with multiple reaction monitoring (MRM) mode of detection.
• Plastic multilayer food packaging materials by LC-Orbitrap-full scan-high resolution mass spectrometry (HRMS) equipped with electrospray ionization (ESI) source.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

Standard for determining aromatic amines released from azo-dyes in commodities

Recommended products

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Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302,H341,H350,H410
• Precautionary Statements: P202 - P264 - P270 - P273 - P301 + P312 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Muta. 2
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves