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Mettler-Toledo Calibration substance ME 30034252, Phenyl salicylate

traceable to primary standards

Synonym(s):

Phenyl salicylate, Salol

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About This Item

Linear Formula:
2-(HO)C6H4CO2C6H5
CAS Number:
Molecular Weight:
214.22
Beilstein:
393969
EC Number:
MDL number:
UNSPSC Code:
20121904
PubChem Substance ID:

grade

analytical standard

Quality Level

shelf life

limited shelf life, expiry date on the label

bp

172-173 °C/12 mmHg (lit.)

mp

41-43 °C (lit.)

application(s)

food and beverages
pharmaceutical

format

neat

SMILES string

Oc1ccccc1C(=O)Oc2ccccc2

InChI

1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H

InChI key

ZQBAKBUEJOMQEX-UHFFFAOYSA-N

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General description

Phenyl salicylate is a carboxylic acid phenyl ester, known for its aroma and flavoring properties. It finds application in foods and consumer products, medicines and as a UV filter.

Mettler-Toledo calibration substance ME 30034252, phenyl salicylate is an analytical standard, intended for use in the regular calibration of Mettler-Toledo melting point instrument. Its melting point value is an average of 6 to 12 iterations with a Mettler-Toledo MP90 Excellence instrument that is calibrated against primary standards. The melting point is measured using Capillary method in conformance with European Pharmacopeia (2.2.14.)

Application

Vanillin Mettler-Toledo calibration substance ME 51143093 is used to calibrate Mettler-Toledo melting point instruments.

Features and Benefits

  • Available in a ready-to-use bottle as a finely ground powder
  • Melting point calibration standard traceable to a primary standard (LGC, London)
  • Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
  • Provided with certificates of analysis and safety sata sheet
  • A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
  • Standard deviation up to ± 0.2 °C

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup


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Simultaneous determination of the UV-filters benzyl salicylate, phenyl salicylate, octyl salicylate, homosalate, 3-(4-methylbenzylidene) camphor and 3-benzylidene camphor in human placental tissue by LC-MS/MS. Assessment of their in vitro endocrine activity
Jimenez-Diaz I, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 80-87 null
D P Krickau et al.
International journal of pharmaceutics, 342(1-2), 62-71 (2007-06-29)
To investigate the influence of the interfacial area and the emulsifier lecithin on the degradation rate of drugs prone to hydrolysis in parenteral lipid O/W emulsions we measured the degradation kinetics of phenyl salicylate in systems consisting of Miglyol as
Phenyl salicylate (Salol) in a lip salve.
C Hindson
Contact dermatitis, 6(3), 216-216 (1980-04-01)
T S Sonnex et al.
Contact dermatitis, 14(5), 268-270 (1986-05-01)
We report 3 cases of allergic contact dermatitis behind the ears from wearing the same brand of industrial safety spectacles. In each case, a positive patch test was obtained with scrapings of the plastic frame. In 2 cases further patch
Allergic contact dermatitis to various salols (phenyl salicylates). A structure-activity relationship study in man and in animal (guinea pig).
B Marchand et al.
Archives of dermatological research, 272(1-2), 61-66 (1982-01-01)

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