Skip to Content
Merck
All Photos(1)

Documents

32810

Sigma-Aldrich

1,4-Diaminobutane dihydrochloride

purum, ≥99.0% (AT)

Synonym(s):

Putrescine dihydrochloride, 1,4-Butanediamine dihydrochloride, 1,4-Diaminobutane dihydrochloride, Tetramethylenediamine dihydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
NH2(CH2)4NH2 · 2HCl
CAS Number:
333-93-7
Molecular Weight:
161.07
Beilstein:
3906680
EC Number:
206-375-9
MDL number:
MFCD00012526
UNSPSC Code:
12352116
PubChem Substance ID:
329754336
NACRES:
NA.22

grade

purum

Quality Level

400

Assay

≥99.0% (AT)

form

powder

mp

280 °C (dec.) (lit.)

solubility

water: soluble 1 g/10 mL, clear, colorless

SMILES string

Cl[H].Cl[H].NCCCCN

InChI

1S/C4H12N2.2ClH/c5-3-1-2-4-6;;/h1-6H2;2*1H

InChI key

XXWCODXIQWIHQN-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

  • Nanocomposite PLA/C20A nanoclay by ultrasound-assisted melt extrusion for adsorption of uremic toxins and methylene blue dye: This study explored the modification of nanoclay with 1,4-diaminobutane dihydrochloride for adsorptive applications, showing enhanced performance in toxin removal (Andrade-Guel et al., 2021).
  • The Total Synthesis of Spermine Alkaloid Kukoamine Bimesylate: This paper details the synthetic route of spermine alkaloid derivatives using 1,4-diaminobutane dihydrochloride, highlighting methods applicable in medicinal chemistry (Dong, 2018).

Biochem/physiol Actions

Binds to the polyamine modulatory site of the NMDA receptor and potentiates NMDA-induced currents; precursor of spermidine.

Pictograms

Skull and crossbonesCorrosion
GHS06,GHS05

Signal Word

Danger

Hazard Statements

H302,H311,H314,H330

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 1

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCH5616
BCCF9152
BCCF9154
BCCF9151
BCCF2125

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Alkylammonium Hexachlorometallates, IV. Synthesis and Crystal Structure of Bis (1, 4-diammoniobutane) Diaquahydrogen Hexachlororhodate (III) Dichloride,[H3N-(CH2) 4-NH3] 2 [H5O2][RhCl6] Cl2.
Frank W and Rei? GJ.
Chemische Berichte, 129(11), 1355-1359 (1996)
Henning Jørgensen et al.
Analytical biochemistry, 317(1), 85-93 (2003-05-06)
Cellulases and hemicellulases are two classes of enzymes produced by filamentous fungi and secreted into the cultivation medium. Both classes of enzymes consist of a subset of classes of which the fungi produce several enzymes with varying molecular mass and
Valeria M Nurchi et al.
Journal of inorganic biochemistry, 194, 26-33 (2019-02-27)
A comprehensive study of the protonation equilibria of a series of polyamine ligands along with their complex formation equilibria with Cu2+ and Zn2+ is reported in this work. The primary aim of this study has been the achievement of homogeneous
J Kirschbaum et al.
Journal of chromatography. A, 881(1-2), 517-530 (2000-07-25)
The reagent 3,5-dinitrobenzoyl chloride (DNBZ-Cl) was tested for pre-column derivatization of biogenic amines (BAs). Samples were derivatized within 3 min in 1 M NaOH at ambient temperature by adding 2-propanole and 50 mM DNBZ-Cl in acetonitrile. The reaction was terminated
Anna Czajkowska-Mysłek et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 105, 82-92 (2017-04-04)
Potential adverse reactions among infants and young children could appear after consumption of food containing small amounts of bioactive amines. This study presents the first assessment of biogenic amines occurrence in ready-to-eat vegetable without/with fish, meat and fruit baby products
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service