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Key Documents

MAB5628

Sigma-Aldrich

Anti-Glial Fibrillary Acidic Protein Antibody

Chemicon®, from mouse

Synonym(s):

GFAP

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

monoclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
western blot: suitable

isotype

IgG2a

NCBI accession no.

NM_002055.2

UniProt accession no.

P14136

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... GFAP(2670)

Application

Detect Glial Fibrillary Acidic Protein using this Anti-Glial Fibrillary Acidic Protein Antibody validated for use in WB & IC.
Western blot: 1:10,000 on rat brain

Optimal working dilutions must be determined by end user.

Linkage

Replaces: 04-1031; 04-1062

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02M phosphate buffer, 0.25 M NaCl, pH 7.6 with 0.1% sodium azide.

Analysis Note

Control
Positive: Neural tissue or astrocyte culture
Negative: Non-neural tissue or neuronal culture

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sitthisak Thongrong et al.
Biomedical reports, 18(3), 20-20 (2023-02-18)
Chronic stress has been recognized to induce the alterations of neuronal and glial cells in the hippocampus, and is thus implicated in cognitive dysfunction. There is increasing evidence to indicate that natural compounds capable of exerting neuroprotective and antioxidant activities
Heather R Minkel et al.
Glia, 63(12), 2285-2297 (2015-07-21)
Alexander Disease (AxD) is a "gliopathy" caused by toxic, dominant gain-of-function mutations in the glial fibrillary acidic protein (GFAP) gene. Two distinct types of AxD exist. Type I AxD affected individuals develop cerebral symptoms by 4 years of age and
Jian-Ying Tian et al.
Experimental and therapeutic medicine, 12(2), 683-689 (2016-07-23)
The aim of the present study was to observe the effects of a general extract of Lycium bararum polysaccharides (LBPs) on methylmercury (MeHg)-induced damage in hippocampus neural stem cells (hNSCs). The hippocampal tissues of embryonic day 16 Sprague-Dawley rats were

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