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Key Documents

MAB2511Z

Sigma-Aldrich

Anti-VCAM-1 Antibody, clone P8B1, Azide Free

clone P8B1, Chemicon®, from mouse

Synonym(s):

CD106, MAB2511

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702

biological source

mouse

Quality Level

100

antibody form

purified antibody

antibody product type

primary antibodies

clone

P8B1, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

isotype

IgG2b

NCBI accession no.

NM_001078.2
NM_080682.1

UniProt accession no.

P19320

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... L1CAM(3897) , VCAM1(7412)

Specificity

MAB2511Z recognizes the human VCAM-1 molecule. The antibody inhibits VLA-4 (integrin alpha4beta1) binding and recognizes a different epitope than that which is recognized by MAB2144 (P3C4 clone).

Application

Anti-VCAM-1 Antibody, clone P8B1, Azide Free is an antibody against VCAM-1.
Function blocking

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Liquid in 0.2 M phosphate buffer to 0.25 M NaCl, pH 7.6, containing no preservatives.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jane Bryant et al.
Arthritis and rheumatism, 64(7), 2137-2146 (2012-01-26)
To examine the migratory properties of cytokine-activated T (Tck) cells. Tck cells were generated by culture of peripheral blood T cells in the presence of interleukin-6 (IL-6), tumor necrosis factor α, and IL-2. Changes in cell surface phenotype were analyzed

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