407709
Insulin, Zinc, Human, Recombinant, P. pastoris
Synonym(s):
Insulin, Zinc, Human, Recombinant, P. pastoris
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About This Item
Recommended Products
sterility
non-sterile
Quality Level
form
solid
specific activity
≥25 IU/mg (dry basis)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
impurities
<10 EU/mg Endotoxin (EU/mg protein)
color
white to off-white
solubility
0.01 M HCl: soluble
shipped in
wet ice
storage temp.
−20°C
InChI key
PBGKTOXHQIOBKM-FHFVDXKLSA-N
Related Categories
General description
Recombinant, human insulin (zinc) expressed in P. pastoris. A peptide anabolic hormone produced by pancreatic β-cells.
Recombinant, human insulin (zinc) expressed in P. pastoris. Peptide anabolic hormone produced by pancreatic β-cells. Increases the synthesis of protein, fat, glycogen, and substrate oxidation in mitochondria. Interacts with membrane insulin receptor to cause its biological actions.
Warning
Toxicity: Standard Handling (A)
Preparation Note
Insulin is practically insoluble from pH 4.5-7.0.
Reconstitution
Following reconstitution store in the refrigerator (4°C). Stock solutions are stable for up to 6 weeks at 4°C.
Other Notes
Mohan, C., et al. 1989. Curr. Topics Cell. Reg.30, 105.
Johnson, I.S. 1983. Science219, 632.
Johnson, I.S. 1983. Science219, 632.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
nwg
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Medha Sharma et al.
Cell communication and signaling : CCS, 20(1), 179-179 (2022-11-16)
The aim of the present study was to determine the role of individual PHLPP isoforms in insulin signaling and insulin resistance in neuronal cells. PHLPP isoforms were either silenced or overexpressed individually, and the effects were observed on individual Akt
Yamini Yadav et al.
The FEBS journal, 289(23), 7561-7581 (2022-07-11)
PP2Cα is one of the newly identified isoforms of metal-dependent protein phosphatases (PPM). The role of this phosphatase in neuronal insulin signalling is completely unknown. In the present study, we show insulin-mediated rapid upregulation of a protein of the insulin
Kapil Manglani et al.
Cell biology international, 46(3), 488-497 (2021-12-06)
Role of CDK5 and its inhibition in various neuronal processes and functions are well established. However, role of CDK5 and its inhibition in neuronal insulin-signaling and-resistance is not yet explored. In the present study, we investigated the effect of CDK5
Kerrie A Morrison et al.
Scientific reports, 12(1), 3532-3532 (2022-03-05)
Extraction of integral membrane proteins with poly(styrene-co-maleic acid) provides a promising alternative to detergent extraction. A major advantage of extraction using copolymers rather than detergent is the retention of the lipid bilayer around the proteins. Here we report the first
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