A-075
Androstenedione solution
1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®
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About This Item
Empirical Formula (Hill Notation):
C19H26O2
CAS Number:
Molecular Weight:
286.41
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
SNAP-N-SPIKE®, SNAP-N-SHOOT®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
concentration
1.0 mg/mL in acetonitrile
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
clinical testing
format
single component solution
storage temp.
−20°C
SMILES string
O=C1C=C2CCC3C4C(C(CC4)=O)(C)CCC3C2(C)CC1
InChI
1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3
InChI key
AEMFNILZOJDQLW-UHFFFAOYSA-N
General description
Androstenedione is a hormone and intermediate in the biochemical pathway for producing testosterone, estrone, and estradiol. This Certified Spiking Solution® is suitable for use as starting material in linearity standards, calibrators, and controls for numerous LC/MS and GC/MS applications in endocrinology, clinical chemistry, neonatal screening, and sports testing.
Application
<ul>
<li><strong>Steroid biosynthesis studies:</strong> The utility of androstenedione solution in dried blood spot analysis via liquid chromatography tandem mass spectrometry is highlighted, providing a method applicable for newborn screening for congenital adrenal hyperplasia and other steroid-related disorders (Zhan et al., 2022).</li>
<li><strong>Hormone precursor biochemical research:</strong> A method for the simultaneous measurement of testosterone, androstenedione, and dehydroepiandrosterone in human serum using liquid chromatography-tandem mass spectrometry was developed, supporting research in hormone biosynthesis and metabolism (Xu et al., 2017).</li>
<li><strong>Anabolic steroid research:</strong> A study on the application of a UHPLC-MS/MS method for the determination of 17 steroidal hormones, including androstenedione, in equine serum, is crucial for advancing research in doping and physiological studies (Genangeli et al., 2017).
</ul>
<li><strong>Steroid biosynthesis studies:</strong> The utility of androstenedione solution in dried blood spot analysis via liquid chromatography tandem mass spectrometry is highlighted, providing a method applicable for newborn screening for congenital adrenal hyperplasia and other steroid-related disorders (Zhan et al., 2022).</li>
<li><strong>Hormone precursor biochemical research:</strong> A method for the simultaneous measurement of testosterone, androstenedione, and dehydroepiandrosterone in human serum using liquid chromatography-tandem mass spectrometry was developed, supporting research in hormone biosynthesis and metabolism (Xu et al., 2017).</li>
<li><strong>Anabolic steroid research:</strong> A study on the application of a UHPLC-MS/MS method for the determination of 17 steroidal hormones, including androstenedione, in equine serum, is crucial for advancing research in doping and physiological studies (Genangeli et al., 2017).
</ul>
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
35.6 °F - closed cup
Flash Point(C)
2 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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