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Sigma-Aldrich

O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol

≥95% (oligomer purity)

Synonym(s):

O-(2-Mercaptoethyl)-O′-(2-carboxyethy)heptaethylene glycol, PEG thiol acid

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About This Item

Empirical Formula (Hill Notation):
C19H38O10S
CAS Number:
Molecular Weight:
458.56
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.22

Assay

≥95% (oligomer purity)

reaction suitability

reagent type: cross-linking reagent

storage temp.

−20°C

SMILES string

OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCS

InChI

1S/C19H38O10S/c20-19(21)1-2-22-3-4-23-5-6-24-7-8-25-9-10-26-11-12-27-13-14-28-15-16-29-17-18-30/h30H,1-18H2,(H,20,21)

InChI key

SKYJRDAORYSCAL-UHFFFAOYSA-N

Application

O-(2-Carboxyethyl)-O′-(2-mercaptoethyl)heptaethylene glycol can be used:
  • To prepare near-infrared fluorochromes applicable in imaging techniques.
  • To functionalize Au nanoparticles for optoelectronic applications.
  • As a linker in the synthesis of antibody-functionalized Au nanoparticles for forensic applications.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Scott A Hilderbrand et al.
Bioconjugate chemistry, 16(5), 1275-1281 (2005-09-22)
In this report, the development of a new class of monocarboxylate functionalized cyanine derivatives using improved synthetic procedures is detailed. The employed synthetic strategy relies on efficient nucleophilic attack of alkyl-thiols on cyanine dyes bearing chloro-substituted polymethinic linkers. Monocarboxylate derivatized
Primiano Pio Di Mauro et al.
International journal of pharmaceutics, 553(1-2), 169-185 (2018-10-16)
A dual-targeting drug delivery system for paclitaxel (PTX) was developed by functionalizing novel polyester-based nanoparticles (NPs) with peptides possessing special affinity for low-density lipoprotein receptor (LDLR), overcoming the limitations of the current chemotherapeutics, to transport drug from blood to brain
Tali Ilovitsh et al.
Scientific reports, 5, 10965-10965 (2015-05-29)
In this paper we present a technique aimed for simultaneous detection of multiple types of gold nanoparticles (GNPs) within a biological sample, using lock-in detection. We image the sample using a number of modulated laser beams that correspond to the
Tali Ilovitsh et al.
Biomedical optics express, 6(4), 1262-1272 (2015-04-25)
Localization microscopy provides valuable insights into cellular structures and is a rapidly developing field. The precision is mainly limited by additive noise and the requirement for single molecule imaging that dictates a low density of activated emitters in the field

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