536938

Biphenyl-4-sulfonyl chloride

• Synonym(s): (4-Biphenylyl)sulfonyl chloride, 4-(Chlorosulfonyl)biphenyl, 4-Phenylbenzenesulfonic acid chloride, 4-Phenylbenzenesulfonyl chloride, p-Biphenylsulfonyl chloride, p-Phenylbenzenesulfonyl chloride
• Linear Formula: C₆H₅C₆H₄SO₂Cl
• CAS Number: 1623-93-4
• Molecular Weight: 252.72
• Beilstein: 2694373
• EC Number: 216-609-1
• MDL number: MFCD00078658
• UNSPSC Code: 12352100
• PubChem Substance ID: 24878182
• NACRES: NA.22

Properties

• form: solid
• Quality Level: 100
• mp: 103-108 °C (lit.)
• SMILES string: ClS(=O)(=O)c1ccc(cc1)-c2ccccc2
• InChI: 1S/C12H9ClO2S/c13-16(14,15)12-8-6-11(7-9-12)10-4-2-1-3-5-10/h1-9H
• InChI key: ALBQXDHCMLLQMB-UHFFFAOYSA-N

Description

Application

Reactant for:

• Preparation of anilinopyrimidinesulfonamides as potential anticancer agents
• Synthesis of inhibitors of the hypoxia inducible factor pathway
• Preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors
• Palladium-catalyzed desulfitative C-arylation

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P305 + P351 + P338 - P310
• Hazard Classifications: Skin Corr. 1B
• Supplementary Hazards: EUH014
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves