43162

2-(Diphenylphosphino)ethylamine

≥95.0% (GC)

• Synonym(s): (2-Aminoethyl)diphenylphosphine, 1-Amino-2-(diphenylphosphino)ethane
• Empirical Formula (Hill Notation): C₁₄H₁₆NP
• CAS Number: 4848-43-5
• Molecular Weight: 229.26
• Beilstein: 644931
• MDL number: MFCD00233831
• UNSPSC Code: 12352116
• PubChem Substance ID: 57650168
• NACRES: NA.22

Properties

• Assay: ≥95.0% (GC)
• form: liquid
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand
• functional group: phosphine
• SMILES string: NCCP(c1ccccc1)c2ccccc2
• InChI: 1S/C14H16NP/c15-11-12-16(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,15H2
• InChI key: RXEPBCWNHKZECN-UHFFFAOYSA-N

Description

General description

2-(Diphenylphosphino)ethylamine is a phosphine ligand that has a bidentate structure with the phosphorus atom donating two lone pair electrons to coordinate with metal atoms. It is used as a reactant to synthesize active catalyst for the selective hydrogenation of amides. In addition, it is also used as a precursor to synthesize other phosphine ligands.

Application

2-(Diphenylphosphino)ethylamine can be used as a bidentate ligand in the nickel catalyst system for the reductive [2+2] cycloaddition reaction to synthesize cyclobutenes from alkynes.

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves