374334
1,1,1,2-Tetrafluoroethane
≥99%
Synonym(s):
HFC-134a
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About This Item
Linear Formula:
FCH2CF3
CAS Number:
Molecular Weight:
102.03
EC Number:
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22
Recommended Products
Assay
≥99%
bp
−26.5 °C (lit.)
functional group
fluoro
SMILES string
FCC(F)(F)F
InChI
1S/C2H2F4/c3-1-2(4,5)6/h1H2
InChI key
LVGUZGTVOIAKKC-UHFFFAOYSA-N
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General description
1,1,1,2-Tetrafluoroethane is used as a trifluorovinylating agent in organic synthesis. It is identified as a potential refrigerant used in place of chlorofluorocarbons. 1,1,1,2-Tetrafluoroethane can also be used as a solvent and medical propellant for a wide range of applications. It is used to extract materials of natural origin like natural flavors, fragrances, and nutraceuticals.
Application
1,1,1,2-Tetrafluoroethane can be used:
- As a solvent in the preparation of cross-linked polymer microspheres through the dispersion polymerization method.
- As a porogenic solvent in the preparation of porous polymethacrylate monolith via free radical polymerization.
- In the synthesis of trifluorovinyllithium, a key intermediate for the preparation of 2-halo-2,3-dideoxy-arabinose derivatives of biological importance.
Packaging
Supplied in a Sure/Pac™ cylinder and has a brass needle valve with a male 1/4" NPTF outlet thread installed. Before using the cylinder, ensure that the valve is closed, then remove the galvanized steel hex cap that seals the outlet valve.
Compatible with the following:
Compatible with the following:
Legal Information
Aldrich is a registered trademark of Sigma-Aldrich Co. LLC
Sure/Pac is a trademark of Sigma-Aldrich Co. LLC
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Press. Gas Compr. Gas
Storage Class Code
2A - Gases
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Parthiban Selvam et al.
Langmuir : the ACS journal of surfaces and colloids, 22(21), 8675-8683 (2006-10-04)
In situ high-pressure tensiometry and ab initio calculations were used to rationally design surfactants for the 1,1,1,2-tetrafluoroethane-water (HFA134a|W) interface. Nonbonded pair interaction (binding) energies (E(b)) of the complexes between HFA134a and candidate surfactant tails were used to quantify the HFA-philicity
Daniel S Yuan et al.
Nucleic acids research, 33(12), e103-e103 (2005-07-05)
A remarkable feature of the Yeast Knockout strain collection is the presence of two unique 20mer TAG sequences in almost every strain. In principle, the relative abundances of strains in a complex mixture can be profiled swiftly and quantitatively by
Stella Papasavva et al.
Environmental science & technology, 43(24), 9252-9259 (2009-12-17)
In response to recent regulations and concern over climate change, the global automotive community is evaluating alternatives to the current refrigerant used in automobile air conditioning units, 1,1,1,2-tetrafluoroethane, HFC-134a. One potential alternative is 2,3,3,3-tetrafluoropropene (HFC-1234yf, also known as HFO-1234yf). We
P D Levin et al.
British journal of anaesthesia, 92(6), 865-869 (2004-05-04)
1,1,1,2 Tetrafluoroethane is a hydrofluoroalkane (HFA) that is replacing chlorofluorocarbons (CFC) as a medical aerosol propellant in an attempt to reduce damage to the ozone layer. This study compared the effects of HFA- and CFC-based inhalers on four anaesthetic gas
Robson P S Peguin et al.
Langmuir : the ACS journal of surfaces and colloids, 22(21), 8826-8830 (2006-10-04)
A combined computational and experimental approach is used to determine the interfacial thermodynamic and structural properties of the liquid 1,1,1,2-tetrafluoroethane (HFA134a)-vapor and liquid HFA134a-water (HFA134a|W) interfaces at 298 K and saturation pressure. Molecular dynamics (MD) computer simulations reveal a stable
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