- APP modulates KCC2 expression and function in hippocampal GABAergic inhibition.
APP modulates KCC2 expression and function in hippocampal GABAergic inhibition.
eLife (2017-01-06)
Ming Chen, Jinzhao Wang, Jinxiang Jiang, Xingzhi Zheng, Nicholas J Justice, Kun Wang, Xiangqian Ran, Yi Li, Qingwei Huo, Jiajia Zhang, Hongmei Li, Nannan Lu, Ying Wang, Hui Zheng, Cheng Long, Li Yang
PMID28054918
ABSTRACT
Amyloid precursor protein (APP) is enriched at the synapse, but its synaptic function is still poorly understood. We previously showed that GABAergic short-term plasticity is impaired in
MATERIALS
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4G10® Platinum, Anti-Phosphotyrosine Antibody, Biotin Conjugate, clone 4G10®, Upstate®, from mouse