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Merck

Provise™ Clearance Services

We understand the importance of your viral clearance study, which is why we are committed to providing a flexible and high quality service. While we handle all the work, you get full transparency, control, and insight into every aspect of the study.


Your Viral Clearance Partner

Our Provise™ Clearance Service deploys a team of highly trained & experienced process scientists and study directors on your behalf, to perform all your required process steps at our state-of-the-art facilities. We will communicate with you to inform you at every step without the need to leave your workplace, maximizing your team’s productivity. You will receive a QA-audited final report to expertly support your regulatory filing.

Our dedicated team leverages extensive experience in:

  • Virus reduction filtration
  • Column chromatography
  • Column re-use studies
  • Ethanol fractionation
  • Viral inactivation by treatment with solvent/detergent and extreme pH
4 Sites Around the Globe

4 Sites Around the Globe

17,300+ Studies Performed

17,300+ Studies Performed

520 Clients Worldwide

520 Clients Worldwide

35 Years Performing Viral Clearance Studies

35 Years Performing Viral Clearance Studies


Working together to deliver your viral clearance study

Your dedicated process team will perform all viral clearance steps on your behalf, keeping you up to date with progress of your study. You will receive a final report and support through your regulatory journey, all while you are doing value-added work within your own facility.

Designing your study

Designing your study

  • Complete the questionnaire
  • Decide execution model for viral clearance study
  • Schedule the slot
  • Finalize study design
    Executing your study
    • Executing your study
    • Finalize technical documents
    • Technical transfers
    • Complete pre-study activity i.e., Cytotoxicity & Spike recovery
    • Complete main study i.e., Chromatography & VRF (Virus Reduction Filtration)
      Finalizing your study
      • Finalizing your study
      • Process & log reduction data compiled
      • Peer & Quality review
      • Delivery of final report
      • Feedback survey

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