Lentiviral Vectors
Enhancing Quality and De-risking Production for Cell & Gene Therapies
Leveraging our deep experience, knowledge, and expertise from three decades of viral vector development and manufacturing, our VirusExpress® lentivirus platform delivers a high performance, high quality solution to de-risk lentivirus production.
Using our VirusExpress® lentivirus platform, our technical experts can accelerate your path to clinical and commercial GMP manufacturing by providing streamlined development, scalable manufacturing, and comprehensive analytics.
Our Track Record
4 x 108 TU/mL
Industry-leading lentivirus titer
< 12
Months to GMP manufacturing
200+ L
Proven, streamlined scalability
300+
Batches of lentiviral vector produced
30
Years of viral vector development and manufacturing
1
One of the first to support commercially approved CAR-Ts
De-risked Lentivirus Production Through Experience
Providing high titer, high yield, and high quality products, our VirusExpress® lentivirus platform has been successfully used in numerous clinical programs.
Partnering with us you gain an efficient and knowledgeable approach, and confidence in the quality of the clinical and commercial manufacturing of your lentiviral vector.
Our lentivirus platform is fully comprehensive and tailored to meet your timelines:
- Packaging and transfer plasmids
- GMP-banked HEK293T cell line
- Chemically defined cell culture medium
- Optimized GMP production
- On-site fill/finish services
- Comprehensive analytical toolbox
- Regulatory support services
Lentivirus VirusExpress® Platform Advantages
Our team of development and manufacturing experts have successfully compressed project timelines and seamlessly scaled-up lentivirus cell and gene therapy programs through IND-submission and into clinical trials.
Proven Performance
- Successfully used in numerous clinical programs
- Multiple INDs in process/filed
Accelerated Timelines
- Less than 12 months to GMP manufacturing
- Save 18 to 20+ months compared to a traditional process timeline
Cost Savings
- Lower operational spend with more productive batches
- Lower cost per dose
Comprehensive Analytics
- In-house analytical testing
- Fully qualified external network
Our Experience is Your Success
Trusted to advance lentiviral cell and gene therapies for three decades, we have the expertise and knowhow to support your therapeutic from preclinical development through commercialization.
Contact us to discover how our lentivirus platform can de-risk and optimize your lentiviral vector program to improve performance, quality, reduce costs, and compress development to GMP manufacturing in less than 12 months.
Related Resources
- Webinar: Streamlining Viral Vector Development and Manufacturing
Hear from our viral vector experts as they showcase our capabilities and solutions for cell and gene therapy production and highlight key features of our technologies and GMP facility.
- Webinar: Industry-leading Lentiviral Titers Through our Optimized VirusExpress® Platform
In this webinar, our innovation scientists explore how they optimized our VirusExpress® platform for lentiviral vectors to maximize titer, while providing a streamlined platform to accelerate development timelines to clinical trials.
- Article: 5 Ways Experience Matters in Gene Therapy Manufacturing
Discover how partnering experienced viral vector CTDMO can help guide you through the complexities of manufacturing and overcome regulatory hurdles to bring new therapies to patients.
- Article: Addressing Manufacturing Challenges in Gene Therapy Development
Learn how our Manufacturability Assessment can help identify and address development and manufacturing challenges when bringing new therapies to market.
- Video: An Optimized & Streamlined Approach for Upstream & Downstream Lentiviral Production
Watch the video and read the poster to learn how we optimized our VirusExpress® platform for lentiviral vectors to maximize titers, enrich recovery, and reduce time to GMP manufacturing.
- White paper: Optimizing and Scaling Lentiviral Vector Production
In this white paper, we outline how DoE studies were used to define and optimize upstream and downstream workflows, establishing the VirusExpress® LV platform as a high quality and performance solution for suspension-based LV vector manufacturing.
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