Bioprocessing Mobius® Single-Use Bioreactors
Whether you are looking to introduce modular single-use bioreactors into your current process or whether you are investigating how you can increase your manufacturing flexibility to accommodate all types of upstream processing (batch, fed-batch, and perfusion processes), Mobius® products and solutions can help you meet your evolving cell culture needs.
The Mobius® Bioreactor family includes the bench scale (2 mL and 3 L), pilot, clinical and commercial manufacturing (50 – 2,000 L) bioreactors that enable cell culturing capabilities from early process development through commercial batch production.
Mobius® single-use bioreactors include products to help you work faster and more cost-effectively. Our experts will partner with you throughout the process to help you meet your goals.
Read More About:
Benchtop Single-Use Bioreactors
Pilot, Clinical & Commercial Single-Use Bioreactors
Mobius® Breez Microbioreactor
2 mL automated single-use perfusion cell culture platform designed to support gentle, adaptable, and reproducible cell processes. The system is capable of accelerating a range of applications such as cell line development, media screening and optimization, and early process development. The Mobius® Breez Microbioreactor allows you to increase efficiency and reduce development timelines and costs over traditional technologies that require more material consumption.
Benefits
- Enables perfusion processes to achieve high cell densities in 2 mL
- Freedom from hands-on work with automated control and monitoring
- Operational flexibility allows you to save on development time and costs
Mobius® 3 L Single-Use Bioreactor
Single-use stirred tank bioreactor for bench-scale cell culture in fed-batch or perfusion mode. It combines the predictability of a stirred tank design with the flexibility of single use, making it the ideal solution for bench scale cell culture process development.
Benefits
- Maximize laboratory resources by saving days of downtime between experiments
- Compatible with wide range of controllers, eliminating the need to purchase additional equipment to switch to a single-use solution
- Comparable functionality to conventional glass bioreactors
Mobius® iFlex Bioreactors
Future-proof your process with modular flexibility today.
Start your transition into the biomanufacturing facility of the future with the Mobius® iFlex Bioreactors—a modular, next-generation, high-performing, perfusion-ready bioreactor, with unparalleled design that can support ultra-high cell densities.
The new Mobius® iFlex Bioreactors are a scalable portfolio of stirred tank bioreactors that leverages single-use bags with enhanced strength, made with our innovative Ultimus® film. Perfusion applications are supported with ease by integrating a perfusion tower, that uses the Cellicon® Filter Assemblies to retain cells in the bioreactor vessel while removing spent media.
Benefits
- High performance with enhanced mixing and oxygen transfer
- Flexibility to fulfill batch, fed-batch and
perfusion processes - Scalability from 50 L to 2000 L
Related Product Resources
- /deepweb/assets/sigmaaldrich/product/documents/254/771/mobius-breez-microbioreactor-ds12130en-ms.pdf
The Mobius® Breez Microbioreactor is a 2 mL automated single-use perfusion cell culture platform designed to support gentle, adaptable, and reproducible cell processes. The system is capable of accelerating a range of applications such as cell line development, media screening and optimization, and early process development.
- Data sheet: Mobius iFlex Bioreactor
The Mobius® iFlex Bioreactor is a scalable family of single-use bioreactors, ranging from 50 L to 2000 L and suitable for process development and commercial manufacturing.
- Application Note: Scalability from Mobius® 3 L Single-Use Bioreactor
Properly scaling from Mobius® 3 L Single-Use Bioreactors to Mobius® iFlex Bioreactors for intensified processes is highly dependent on maintaining mixing, oxygenation, nutrient, and process control.
- Data Sheet: Mobius® CellReady 3 L Bioreactor
The Mobius® CellReady 3 L bioreactor is a convenient and cost-effective tool for the culture of clinical grade human mesenchymal stem cells (hMSCs). Popular multi-layer flatbed culture expansion techniques are cumbersome, time consuming and do not allow a constant monitoring of cells during the manufacturing process.
Related Webinars
The ability to scale down upstream intensified processes has been limited due to lack of appropriate technologies. This webinar describes a new 2mL single-use perfusion microbioreactor system that fulfills this throughput-performance gap.
Learn about the advantage of adopting a perfusion-specific CLD process to create more productive clones, and find solutions for intensified processing using CHOZN® GS-/- cell line, a suite of best-in-class media, and Mobius® Breez Microbioreactor.
In this webinar, you will learn how our new single-use bioreactor family can help you fulfill any process strategy, be it batch, fed-batch, or perfusion, and facilitate scalability of your upstream process, to reduce production costs.
*System Service Reliance Plan not applicable to Mobius® 3 L Bioreactor
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