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Merck

TNNC1

troponin C type 1 (slow)

Synonyms:
CMD1Z, CMH13, TN-C, TNC, TNNC
Species:
UniProtKB ID:
Gene ID:
  • Human(7134) Summary: Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]
  • Mouse(21924) troponin C, cardiac/slow skeletal
  • Rat(290561) troponin C type 1 (slow)
  • chicken(396032) troponin C type 1 (slow)
  • domestic cat(101082986) troponin C type 1 (slow)
  • dog(476595) troponin C type 1 (slow)
  • cow(509486) troponin C type 1 (slow)
  • sheep(101111132) troponin C type 1 (slow)
  • Goat(100860954) troponin C type 1 (slow)
  • domestic guinea pig(100730526) troponin C type 1 (slow)
  • naked mole-rat(101702386) troponin C type 1 (slow)

Custom & Knockdown Gene Products

  • siRNA

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ELISA

Product Number
Description
Species
Human Troponin C ELISA, for serum, plasma and cell culture supernatants,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
Levosimendan, ≥98% (HPLC),
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TNNC1 antibody produced in mouse, clone 1F8-A9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry

western blot
Anti-TNNC1 Antibody, clone 8Z4V9, Rabbit Monoclonal, ,
Species Reactivity
mouse, rat
Application
western blot
Anti-TNNC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TNNC1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TNNC1,
Species
human
MISSION® esiRNA, targeting mouse Tnnc1,
Species
mouse