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Merck

TLR8

toll-like receptor 8

Synonyms:
CD288
Species:
UniProtKB ID:
Gene ID:
  • Human(51311) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170744) toll-like receptor 8
  • Rat(684440) toll-like receptor 8
  • Zebrafish(100334317) toll-like receptor 8
  • dog(100684828) toll-like receptor 8
  • Horse(100054367) toll-like receptor 8
  • domestic cat(493658) toll-like receptor 8
  • domestic guinea pig(100713058) toll-like receptor 8
  • naked mole-rat(101726643) toll-like receptor 8
  • Domestic Rabbit(100328930) toll-like receptor 8
  • cow(532262) toll-like receptor 8
  • sheep(554259) toll-like receptor 8
  • Goat(100860909) toll-like receptor 8

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-TLR8 antibody produced in mouse, clone 1E6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Anti-Mouse Tlr8 (C-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
immunohistochemistry
Monoclonal Anti-TLR8 antibody produced in mouse, clone 4C6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
ANTI-MOUSE TLR8 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
Anti-TLR8 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TLR8,
Species
human
MISSION® esiRNA, targeting mouse Tlr8,
Species
mouse