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Merck

PCDHGA1

protocadherin gamma subfamily A, 1

Synonyms:
PCDH-GAMMA-A1
Species:
UniProtKB ID:
Gene ID:
  • Human(56114) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • Mouse(93709) protocadherin gamma subfamily A, 1
  • Rat(553129) protocadherin gamma subfamily A, 1
  • cow(786935) protocadherin gamma subfamily A, 1
  • sheep(101104745) protocadherin gamma subfamily A, 1
  • Horse(100072267) protocadherin gamma subfamily A, 1
  • domestic cat(101096946) protocadherin gamma subfamily A, 1
  • dog(607510) protocadherin gamma subfamily A, 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-Protocadherin Gamma (Pan) antibody produced in mouse, clone S159-5, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Protocadherin Gamma (Pan) - Atto 594 antibody produced in mouse, clone S159-5, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Protocadherin Gamma (Pan) - Atto 390 antibody produced in mouse, clone S159-5, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Protocadherin Gamma (Pan) - Rpe antibody produced in mouse, clone S159-5, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-Protocadherin Gamma (Pan) - Atto 488 antibody produced in mouse, clone S159-5, purified immunoglobulin,
Species Reactivity
mouse, rat
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
PrEST Antigen PCDHGA1, Prestige Antigens Powered by Atlas Antibodies, buffered aqueous solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PCDHGA1,
Species
human