P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
Synonyms:
P2X7
Species:
Human P2RX7 (5027), Mouse P2rx7 (18439), Rat P2rx7 (29665), Zebrafish p2rx7 (387298), chicken P2RX7 (771952), cow P2RX7 (286814), domestic cat P2RX7 (101097922), Horse P2RX7 (100058464), dog P2RX7 (448778), domestic guinea pig P2rx7 (100379234) ...More
UniProtKB ID:
Gene ID:
- Human(5027) Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010]
- Mouse(18439) purinergic receptor P2X, ligand-gated ion channel, 7
- Rat(29665) purinergic receptor P2X, ligand-gated ion channel, 7
- Zebrafish(387298) purinergic receptor P2X, ligand-gated ion channel, 7
- chicken(771952) purinergic receptor P2X, ligand-gated ion channel, 7
- cow(286814) purinergic receptor P2X, ligand-gated ion channel, 7
- domestic cat(101097922) purinergic receptor P2X, ligand-gated ion channel, 7
- Horse(100058464) purinergic receptor P2X, ligand-gated ion channel, 7
- dog(448778) purinergic receptor P2X, ligand-gated ion channel, 7
- domestic guinea pig(100379234) purinergic receptor P2X, ligand-gated ion channel, 7
- naked mole-rat(101721795) purinergic receptor P2X, ligand-gated ion channel, 7
- Domestic Rabbit(100351535) purinergic receptor P2X, ligand-gated ion channel, 7
- sheep(101103842) purinergic receptor P2X, ligand-gated ion channel, 7
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-P2RX7 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-P2RX7 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse, rabbit
Application
immunohistochemistry
western blot
western blot
Anti-P2RX7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-P2X7 Antibody, clone 1D23-1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human
Application
ELISA
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
Anti-P2RX7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
esiRNA
Product Number
Description
Species