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Merck

IPO7

importin 7

Synonyms:
Imp7, RANBP7
Species:
UniProtKB ID:
Gene ID:
  • Human(10527) Summary: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008]
  • Mouse(233726) importin 7
  • Rat(308939) importin 7
  • domestic guinea pig(100731817) importin 7
  • naked mole-rat(101702324) importin 7
  • sheep(101105184) importin 7
  • Domestic Rabbit(100345214) importin 7
  • Zebrafish(321739) importin 7
  • cow(513707) importin 7
  • Horse(100055677) importin 7
  • domestic cat(101091652) importin 7
  • dog(485383) importin 7
  • chicken(423046) importin 7

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-IPO7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Monoclonal Anti-IPO7, (C-terminal) antibody produced in mouse, clone 4G6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-IPO7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ipo7,
Species
mouse
MISSION® esiRNA, targeting human IPO7,
Species
human