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Merck

CRHR1

corticotropin releasing hormone receptor 1

Synonyms:
CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRH-R1h, CRHR, CRHR1L, CRHR1f
Species:
UniProtKB ID:
Gene ID:
  • Human(1394) Summary: This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346. [provided by RefSeq, Jan 2012]
  • Mouse(12921) corticotropin releasing hormone receptor 1
  • Rat(58959) corticotropin releasing hormone receptor 1
  • sheep(443025) corticotropin releasing hormone receptor 1
  • Domestic Rabbit(100302436) corticotropin releasing hormone receptor 1
  • domestic guinea pig(100729987) corticotropin releasing hormone receptor 1
  • naked mole-rat(101721828) corticotropin releasing hormone receptor 1
  • Zebrafish(567940) corticotropin releasing hormone receptor 1
  • cow(281716) corticotropin releasing hormone receptor 1
  • Horse(100065598) corticotropin releasing hormone receptor 1
  • chicken(374218) corticotropin releasing hormone receptor 1
  • dog(610380) corticotropin releasing hormone receptor 1
  • domestic cat(723971) corticotropin releasing hormone receptor 1
  • domestic cat(101089308) corticotropin releasing hormone receptor 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Small Molecule - Antagonist

Product Number
Description
Species
NBI 27914, ≥98% (HPLC),
Species
human
2,2′:5′,2′′:5′′,2′′′-Quaterthiophene, 96%,
Species
human, rat, mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Corticotropin-Releasing Factor Receptor 1 Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
immunohistochemistry
Anti-CRHR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-CRHR1/CRF-R (AA 107-117) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
ANTI-CRFR1 (Q103) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
western blot
Anti-CRFR1/CRHR1 Antibody, clone 1N21 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunocytochemistry

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Crhr1,
Species
mouse
MISSION® esiRNA, targeting human CRHR1,
Species
human