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Merck

CHRNB3

cholinergic receptor, nicotinic, beta 3 (neuronal)

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(1142) Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]
  • Mouse(108043) cholinergic receptor, nicotinic, beta polypeptide 3
  • Rat(171131) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • chicken(395604) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • cow(521702) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Horse(100054095) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • dog(482837) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic cat(101098624) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • sheep(101122833) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Domestic Rabbit(100355898) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • naked mole-rat(101706291) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic guinea pig(100723424) cholinergic receptor, nicotinic, beta 3 (neuronal)

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Small Molecule - Agonist

Product Number
Description
Species
Decamethonium bromide, crystalline,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat

Small Molecule - Antagonist

Product Number
Description
Species
Mecamylamine hydrochloride, ,
Species
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Species
human, rat
Kynurenic acid, ≥98%,
Species
rat, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-CHRNB3 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
Anti-CHRNB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Blocker

Product Number
Description
Species
Hexamethonium bromide, ,
Species
human
Hexamethonium chloride, solid (hygroscopic),
Species
human
Tetraethylammonium chloride, ≥98% (titration),
Species
human
Kynurenic acid, ≥98%,
Species
rat, human

Proteins

Product Number
Description
Species
Buserelin acetate salt, ≥90% (HPLC),
Species
rat