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USP

Polydimethylsiloxane

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Dimethylpolysiloxane, Dimethylsiloxane, Silicone oil, Polydimethylsiloxane

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

polydimethylsiloxane

mol wt

71800-547100 g/mol

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C2H6OSi/c1-4(2)3/h1-2H3

InChI key

SEUDSDUUJXTXSV-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Polydimethylsiloxane USP reference standard suitable for use in specified USP compendial tests and assays.

Also used to prepare standard preparation, standard and standard stock solution for the assay according to the given below general chapters and monographs of United States Pharmacopeia (USP):
  • Calcium Carbonate, Magnesia, and Simethicone Chewable Tablets
  • Simethicone Oral Suspension
  • Simethicone Capsules
  • Dimethicone
  • Simethicone
Clear, colorless fluid polymer useful as a stationary phase in gas chromatography and as an anti-foaming agent.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

609.8 °F - closed cup

Flash Point(C)

321 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Simethicone Capsules
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 33(5), 4043-4043 (2020)
Molecular weight distribution of poly (dimethylsiloxane) by combining matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with gel-permeation chromatography fractionation.
Montaudo, Giorgio, et al.
Rapid Communications in Mass Spectrometry, 9.12, 1158-1163 (1995)
Robust and biodegradable elastomers based on corn starch and polydimethylsiloxane (PDMS).
Ceseracciu L
ACS Applied Materials & Interfaces, 7(6), 3742-3753 (2015)

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