SML3548
8RK64
≥98% (HPLC)
Synonym(s):
(S)-N-(5-(2-azidoacetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)-1-cyanopyrrolidine-3-carboxamide
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About This Item
Empirical Formula (Hill Notation):
C14H16N8O2S
CAS Number:
Molecular Weight:
360.39
UNSPSC Code:
12352200
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Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=C([C@H]1CCN(C#N)C1)NC2=NC3=C(S2)CN(C(CN=[N+]=[N-])=O)CC3
Biochem/physiol Actions
8RK64 is a cell penetrant, potent and selective covalent inhibitor of UCHL1 (ubiquitin carboxy-terminal hydrolase L1) that binds to the active-site cysteine residue of UCHL1. 8RK64 potently inhibits UCHL1 activity in cells.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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