SML3347

NPSP795 hydrochloride

≥95% (HPLC)

• Synonym(s): (R)-3-(4-Cyano-3-(3-((1-(2,3-dihydro-1H-inden-2-yl)-2-methylpropan-2-yl)amino)-2-hydroxypropoxy)phenyl)propanoic acid hydrochloride, 4-Cyano-3-[(2R)-3-[[2-(2,3-dihydro-1H-inden-2-yl)-1,1-dimethylethyl]amino]-2-hydroxypropoxy]benzenepropanoic acid hydrochloride, SB-423562 hydrochloride, SHP635
• Empirical Formula (Hill Notation): C₂₆H₃₂N₂O₄ · xHCl
• Molecular Weight: 436.54 (free base basis)
• MDL number: MFCD19443794
• UNSPSC Code: 12352200

Properties

• Quality Level: 100
• Assay: ≥95% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear (Warmed)
• storage temp.: -10 to -25°C
• SMILES string: O=C(O)CCC1=CC=C(C#N)C(OC[C@H](O)CNC(C)(C)CC2CC3=C(C=CC=C3)C2)=C1

Description

Biochem/physiol Actions

NPSP795 is a calcium-sensing receptor negative allosteric modulator (CaSR NAMs). NPSP795 suppress airway hyperresponsiveness and inflammation in human cells and murine asthma surrogates. It does not alter blood pressure, heart rate or serum calcium concentrations.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable