SML1926
GAT211
≥98% (HPLC)
Synonym(s):
3-(2-Nitro-1-phenylethyl)-2-phenyl-1H-indole
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About This Item
Empirical Formula (Hill Notation):
C22H18N2O2
CAS Number:
Molecular Weight:
342.39
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 10 mg/mL, clear
storage temp.
2-8°C
SMILES string
O=[N+]([O-])CC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3)NC4=CC=CC=C42
Biochem/physiol Actions
GAT211 is a positive allosteric modulator (PAM) of cannabinoid CB1 receptor signaling. GAT211 was found to amplify the therapeutic effect of endocannabinoids without the negative side effects of psychoactivity or tolerance. GAT211 caused a CB1-dependent suppression of paclitaxel-induced mechanical and cold allodynia with no sign of tolerance over 19 days of administration.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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