SAB5500087

Anti-COX2 antibody, Rabbit monoclonal

clone SP21, recombinant, expressed in proprietary host, tissue culture supernatant

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• recombinant: expressed in proprietary host
• conjugate: unconjugated
• antibody form: tissue culture supernatant
• antibody product type: primary antibodies
• clone: SP21, monoclonal
• species reactivity: human (tested)
• species reactivity (predicted by homology): mouse, frog, bovine, rat, dog
• technique(s): immunohistochemistry: 1:100
• isotype: IgG
• UniProt accession no.: P35354
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: human ... PTGS2(5743)

Description

General description

COX-2 (Cyclooxygenase-2) is an inducible enzyme. It is involved in the response of cells to growth factors, tumor promoters, and cytokines that induce its expression. Given its role in synthesizing prostaglandins, COX-2 is therefore of interest in studying immune response regulation. COX-2 is induced by a wide variety of stimuli and was initially identified as immediate-early growth response gene. In addition, COX-2 expression markedly increased in 85-90% of human colorectal adenocarcinoma whereas COX-1 levels remain unchanged.

Immunogen

Synthetic peptide corresponding to C-terminus of rat COX-2.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody supplied as tissue culture supernatant in TBS/1% BSA buffer pH 7.5 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable