SAB4503194

Anti-Calmodulin antibody produced in rabbit

affinity isolated antibody

• Synonym(s): CALM, CALM1, CALM2, CALM3, CAM
• MDL number: MFCD00162206
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 16 kDa
• species reactivity: human, rat, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:1000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI accession no.: P62158
• UniProt accession no.: P0DP23
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... CALM1(801)

Description

General description

Anti-Calmodulin Antibody detects endogenous levels of total Calmodulin protein.
Calmodulin (CaM), a highly conserved Ca²⁺-binding protein, is mapped to human chromosome 14q32. Calmodulin is a small protein abundantly present in the brain and coded by three genes (CALM1-3).

Immunogen

The antiserum was produced against synthesized peptide derived from human Calmodulin.

Immunogen Range: 46-95

Application

Anti-Calmodulin antibody has been used in western blotting.

Biochem/physiol Actions

Calmodulin (CaM) possesses Ca²⁺-dependent modulatory roles. It participates in cell proliferation and muscle activity. Calmodulin plays a major role in catecholaminergic polymorphic ventricular tachycardia (CPVT) and in long QT syndrome (LQTS). This protein modulates the transcriptional processes required for proper heart function.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable