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Key Documents

SAB3701437

Sigma-Aldrich

Monoclonal Anti-HSP27 antibody produced in mouse

clone G3.1, purified immunoglobulin

Synonym(s):

Anti-Heat shock 27 kDa protein antibody, Anti-Heat shock cognate protein 71-kDa antibody, Anti-HspB1 antibody, Anti-SRP27 antibody, Anti-Stress-responsive protein 27 antibody

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

G3.1, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

ELISA: suitable
western blot: suitable

isotype

IgG1κ

UniProt accession no.

P04792

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... HSPB1(3315)

Specificity

This protein A purified mouse monoclonal antibody reacts specifically with HSP27 in human tissues and cell lines.  MCF-7 cells are recommended as a positive control.  Cross reactivity with hsp27 from other mammalian sources is likely.  No cross reactivity occurs with HSP70, HSP90 or HSP104.

Immunogen

Prokaryotic recombinant protein corresponding to the full length human hsp27 protein.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in 0.02 M Potassium Phosphate, 0.5 M Sodium Chloride, pH 7.2 with 0.01% (w/v) Sodium Azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Jihad Karam et al.
Molecular and clinical oncology, 7(5), 808-814 (2017-11-29)
Late detection and lack of standard treatment strategies in larynx cancer patients result in high levels of mortality and poor prognosis. Prognostic stratification of larynx cancer patients based on molecular prognostic tumor biomarkers may lead to more efficient clinical management.
Lin Xue et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 35(7), 6999-7007 (2014-04-22)
Previous studies have indicated that heat shock protein 27 (HSP27) had high correlation with the development and progression in several tumors. However, the roles of HSP27 in esophageal squamous cell carcinoma (ESCC) were uncertain. The aim in this study is

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