GW21222

Anti-c-Myc (ab2) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-Myc proto-oncogene protein
• MDL number: MFCD00239651
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: chicken
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: mouse, rat, human
• manufacturer/tradename: Genway 15-288-21222
• technique(s): western blot: suitable
• NCBI accession no.: NP_002458.1
• UniProt accession no.: P01106
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... MYC(4609)

Description

Immunogen

Immunogen Sequence: GI # 12962935, sequence 268-386

Recombinant V-myc myelocytomatosis viral oncogene homolog

Application

Anti-c-Myc (ab2) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Myc (c-Myc) is a regulatory gene and encodes for a transcription factor. It is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. Myc is associated with aggressive behaviour in several cancers. c-MYC gain with lung adenocarcinoma is a candidate for additional first-line treatment to mitigate increased risk for disease progression and death. It plays an important role in the pathogenesis of B-cell prolymphocytic leukemia (B-PLL).

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves