G9270
γ-Glutamyltranspeptidase from equine kidney
Type VI, 5-12 units/mg solid
Synonym(s):
γ-GT, γ-Glutamyltransferase, (5-Glutamyl)peptide:amino-acid 5-glutamyltransferase, GGTP
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About This Item
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biological source
equine kidney
Quality Level
type
Type VI
form
solid
specific activity
5-12 units/mg solid
storage temp.
−20°C
General description
Gamma-Glutamyltranspeptidase is a heterodimeric enzyme and belongs to the superfamily of N-terminal nucleophile hydrolases.
Application
Gamma-glutamyltranspeptidase from equine kidney has been used:
- to identify the formation of 4-S-Cysteinyltetrodotoxin in the liver of Fugu pardalis
- as a standard to determine the activity of gamma-glutamyltransferase from human B-cell lymphoma cell lysates
- to hydrolyze isopeptides to study its effects on tubulin aggregation
Biochem/physiol Actions
Gamma-Glutamyltranspeptidase participates in glutathione metabolism and it catalyzes the cleavage of gamma-glutamyl compounds, such as glutathione. It also plays a role in the transfer of gamma-glutamyl moiety to amino acids and peptides.
Quality
Crude
Unit Definition
One unit will liberate 1.0 μmole of p-nitroaniline from L-γ-glutamyl-p-nitroanilide per min at pH 8.5 at 25°C.
inhibitor
Product No.
Description
Pricing
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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