N8280

Naproxen

meets USP testing specifications

• Synonym(s): (S)-(+)-6-Methoxy-α-methyl-2-naphthaleneacetic acid, (S)-(+)-2-(6-Methoxy-2-naphthyl)propionic acid
• Linear Formula: CH₃OC₁₀H₆CH(CH₃)CO₂H
• CAS Number: 22204-53-1
• Molecular Weight: 230.26
• Beilstein: 3591068
• EC Number: 244-838-7
• MDL number: MFCD00010500
• UNSPSC Code: 12352200
• PubChem Substance ID: 24897861
• NACRES: NA.21

Properties

• Agency: USP/NF; meets USP testing specifications
• Quality Level: 200
• form: powder
• mp: 152-154 °C (lit.)
• application(s): pharmaceutical (small molecule)
• SMILES string: COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O
• InChI: 1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1
• InChI key: CMWTZPSULFXXJA-VIFPVBQESA-N
• Gene Information: human ... MAPK14(1432) , PTGS1(5742) , PTGS2(5743) ; rat ... Alox5(25290) , Ptgs1(24693)

Description

Biochem/physiol Actions

Non-selective cyclooxygenase (COX-1 and COX-2) inhibitor.

Safety Information

• Pictograms: GHS08,GHS07,GHS09
• Signal Word: Warning
• Hazard Statements: H302,H315,H319,H335,H361fd,H411
• Precautionary Statements: P202 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3