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46834

Supelco

Sulfameter

VETRANAL®, analytical standard

Synonym(s):

5-Methoxysulfadiazine, N1-(5-Methoxypyrimidin-2-yl)sulfanilamide, Sulfamethoxydiazine

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About This Item

Empirical Formula (Hill Notation):
C11H12N4O3S
CAS Number:
651-06-9
Molecular Weight:
280.30
Beilstein:
621130
EC Number:
211-480-8
MDL number:
MFCD00006067
UNSPSC Code:
41116107
PubChem Substance ID:
329757247
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1

InChI

1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)

InChI key

GPTONYMQFTZPKC-UHFFFAOYSA-N

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General description

Chemical structure: sulfonamide
Sulfameter is a long-acting sulfonamide, which is found to be effective on urinary and respiratory tract infections. It is often used for animal disease treatment and prevention.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfameter may be used as a reference standard in the determination of sulfameter in water samples and natural animal casings using solid phase extraction with high-performance liquid chromatography coupled with an ultraviolet detector (SPR-HPLC-UV).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF9470
BCCD6687
BCBX3995
BCBW1230
BCBR9658V

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Quantitative analysis of sulfonamide residues in natural animal casings by HPLC.
Sun H, et al.
Chromatographia, 66(5-6), 333-337 (2007)
Analysis of sulfonamides in environmental water samples based on magnetic mixed hemimicelles solid-phase extraction coupled with HPLC-UV detection.
Sun L, et al.
Chemosphere, 77(10), 1306-1312 (2009)
Studies of sulfamethoxydiazine.
Chew HW, et al.
Clinical Pharmacology and Therapeutics, 6(3), 307-315 (1965)
H S Kaumeier
Arzneimittel-Forschung, 30(10), 1794-1800 (1980-01-01)
It is demonstrated that the bioavailability of sulfamethoxydiazine (Durenat), taken as an example, is much better when administered simultaneously with a test meal than when given in the fasting state. Also a high-lipid meal in comparison with a high-protein or
S Kaumeier
International journal of clinical pharmacology and biopharmacy, 17(6), 260-263 (1979-06-01)
The present investigation is concerned with the influence of the composition of food on the absorption of sulfameter. Six physically healthy patients each were given 2 g of sulfameter simultaneously with a high lipid, high protein and high carbohydrate test
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