46207

Diethylstilbestrol

VETRANAL^®, analytical standard

• Synonym(s): (E)-3,4-Bis(4-hydroxyphenyl)-3-hexene, DES, Stilbestrol
• Empirical Formula (Hill Notation): C₁₈H₂₀O₂
• CAS Number: 56-53-1
• Molecular Weight: 268.35
• Beilstein: 2056095
• EC Number: 200-278-5
• MDL number: MFCD00002373
• UNSPSC Code: 41116107
• PubChem Substance ID: 329757101
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 200
• product line: VETRANAL^®
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2
• InChI: 1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
• InChI key: RGLYKWWBQGJZGM-ISLYRVAYSA-N
• Gene Information: human ... ESR1(2099)

Description

General description

Diethylstilbestrol (DES) belongs to the synthetic oestrogens class of compounds.

Application

DES has been used as a reference standard for the determination of DES in:

• Dairy products by QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure and ultra-high performance liquid chromatography-triple quadrupole mass spectrometry (UHPLC-QqQ MS/MS) equipped with electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode of detection.
• Water samples by magnetic micro-dispersive solid-phase extraction (m-μSPE) and HPLC-MS.

It may be used as a reference standard for the analysis of DES in

• Aquatic products by modified QuEChERS extraction and multiplug filtration clean-up (m-PFC) followed by LC-ESI-MS/MS with MRM mode of detection.
• Milk samples by vortex-assisted hollow fibre liquid-phase microextraction (VA-HF-LPME) and HPLC with diode array detection (HPLC-DAD).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07,GHS08,GHS09
• Signal Word: Danger
• Hazard Statements: H315 - H319 - H335 - H350 - H360FD - H410
• Precautionary Statements: P202 - P261 - P273 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves