538909

Prostaglandin D₂

Major prostaglandin metabolite in brain and an important inflammatory mediator in mast cells.

• Synonym(s): Prostaglandin D₂, PGD₂
• Empirical Formula (Hill Notation): C₂₀H₃₂O₅
• CAS Number: 41598-07-6
• Molecular Weight: 352.47
• MDL number: MFCD00077857
• UNSPSC Code: 12352211

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white
• solubility: ethanol: 100 mg/mL; acetone: soluble; ethyl acetate: soluble; methanol: soluble
• shipped in: wet ice
• storage temp.: −20°C
• InChI: 1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-/m0/s1
• InChI key: BHMBVRSPMRCCGG-OUTUXVNYSA-N

Description

General description

Major prostaglandin metabolite in the brain and an important inflammatory mediator in mast cells. Neuromodulator that evokes nerve-mediated Cl^- secretion. Stimulates adenylate cyclase.

Biochem/physiol Actions

Cell permeable: no

Primary Target
Adenylate cyclase

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C).

Other Notes

Horn, E.H., et al. 1995. Clin. Sci. 89, 91.
Frieling, T., et al. 1994. Am. J. Physiol. 266, G132.
Huttemeier, P.C., et al. 1993. Prostaglandins 45, 177.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H360
• Precautionary Statements: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 1B
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable