1.08883

Zinc sulfate heptahydrate

for analysis EMSURE^® ACS,ISO,Reag. Ph Eur

• Synonym(s): Zinc
• Linear Formula: ZnSO₄ · 7H₂O
• CAS Number: 7446-20-0
• Molecular Weight: 287.56
• MDL number: MFCD00149894
• UNSPSC Code: 12352302
• EC Index Number: 231-793-3

Properties

• grade: ACS reagent
• Quality Level: 300
• Agency: reag. ISO; reag. Ph. Eur.; suitable for SM 5210
• product line: EMSURE^®
• Assay: 99.5-103.0% (complexometric)
• form: solid
• potency: 1260 mg/kg LD₅₀, oral (Rat)
• impurities: ≤0.01% Insoluble matter
• pH: 4-6 (20 °C, 50 g/L in H₂O)
• mp: 100 °C
• solubility: 965 g/L
• density: 1.97 g/cm³ at 20 °C
• bulk density: 800‑1000 kg/m³
• anion traces: chloride (Cl^-): ≤0.0005%; nitrate (NO₃^-): ≤0.002%
• cation traces: As: ≤0.00005%; Ca: ≤0.001%; Cd: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.001%; Mg: ≤0.001%; Mn: ≤0.0003%; N: ≤0.0005%; NH₄⁺: ≤0.001%; Na: ≤0.001%; Pb: ≤0.001%
• storage temp.: 2-30°C
• SMILES string: O.O.O.O.O.O.O.[Zn++].[O-]S([O-])(=O)=O
• InChI: 1S/H2O4S.7H2O.Zn/c1-5(2,3)4;;;;;;;;/h(H2,1,2,3,4);7*1H2;/q;;;;;;;;+2/p-2
• InChI key: RZLVQBNCHSJZPX-UHFFFAOYSA-L

Description

Application

• Validation of a simple liquid chromatography coupled to tandem mass spectrometry method for the simultaneous determination of tacrolimus, sirolimus, everolimus and cyclosporin A in dried matrix on paper discs.: This study validates a liquid chromatography-mass spectrometry method enhanced by zinc sulfate heptahydrate for analyzing immunosuppressant drugs. This development represents a significant advance in clinical diagnostics, providing faster and more reliable drug monitoring (Bressán et al., 2021).


• Adduct simplification in the analysis of cyanobacterial toxins by matrix-assisted laser desorption/ionization mass spectrometry.: Research utilizing zinc sulfate heptahydrate in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry to simplify the analysis of cyanobacterial toxins. This study enhances the understanding of environmental toxins, showcasing the role of zinc sulfate heptahydrate in improving analytical accuracy and efficiency (Howard et al., 2007).

Linkage

Replaces: ZX0105; ZX0105-1; ZX0105-20

Analysis Note

Assay (complexometric): 99.5 - 103.0 %
Identity: passes test
Appearance of solution: passes test
Insoluble matter: ≤ 0.01 %
pH-value (5 %; water, 25 °C): 4.4 - 5.6
Chloride (Cl): ≤ 0.0005 %
Total nitrogen (N): ≤ 0.0005 %
Nitrate (NO₃): ≤ 0.002 %
As (Arsenic): ≤ 0.00005 %
Ca (Calcium): ≤ 0.001 %
Cd (Cadmium): ≤ 0.0005 %
Cu (Copper): ≤ 0.0005 %
Fe (Iron): ≤ 0.0005 %
K (Potassium): ≤ 0.001 %
Mg (Magnesium): ≤ 0.001 %
Mn (Manganese): ≤ 0.0003 %
Na (Sodium): ≤ 0.001 %
NH₄ (Ammonium): ≤ 0.001 %
Pb (Lead): ≤ 0.001 %
Corresponds to ACS, ISO, Reag. Ph Eur

Legal Information

EMSURE is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS05,GHS07,GHS09
• Signal Word: Danger
• Hazard Statements: H302 - H318 - H410
• Precautionary Statements: P264 - P270 - P273 - P280 - P301 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable