QBD10201

Biotin-dPEG^®₃-MAL

• Synonym(s): Polyethylene glycol
• Empirical Formula (Hill Notation): C₂₇H₄₃N₅O₈S
• Molecular Weight: 597.72
• UNSPSC Code: 51171641
• PubChem Substance ID: 329823891
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: thiol reactive; reagent type: linker
• polymer architecture: shape: linear; functionality: monofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C(NCCCOCCOCCOCCCNC(CCCCC1C2NC(NC2CS1)=O)=O)CCN3C(C=CC3=O)=O

Description

Application

Biotin-dPEG^®₃-MAL can be used as a cross-linking reagent in biotinylation reaction.

Features and Benefits

Biotin-dPEG^®₃-MAL takes advantage of the well-known, specific Michael reaction between a maleimide group and a free sulfhydryl to allow site-specific biotin labeling of molecules in aqueous media within the pH range of 6.5 – 7.5. The single molecular weight dPEG^® spacer (24.9 Å) provide precise spacing between the biotin moiety and the labeled molecule. The dPEG^® spacer imparts water solubility to the labeled molecule while reducing immunogenicity, aggregation, and precipitation of labeled biomolecules or other labeled compounds.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable