Skip to Content
Merck
All Photos(2)

Key Documents

More Documents

ALD00596

Sigma-Aldrich

N-((1S,2S)-1-(3,5-Di-tert-butylphenyl)-2-(quinolin-2-yl)butyl)acetamide

≥95%

Synonym(s):

Chiral acetyl-protected aminoethyl quinoline ligand, Et-APAQ

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C29H38N2O
Molecular Weight:
430.62
MDL number:
MFCD30830353
UNSPSC Code:
12352200

Quality Level

100

Assay

≥95%

form

powder or crystals

reaction suitability

reaction type: C-C Bond Formation
reagent type: catalyst
reagent type: ligand
reaction type: C-H Activation

Related Categories

Application

This chiral acetyl-protected aminoethyl quinoline (APAQ) ligand was developed by the Yu group for ligand-enabled acceleration of Pd-catalyzed enantioselective β-methylene C–H functionalization, which is important for the generation of β-chiral centers in asymmetric synthesis.

Other Notes

Ligand-accelerated enantioselective methylene C(sp3)–H bond activation

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Related Content

Yu Group – Professor Product Portal

The Yu program centers around the discovery of catalytic carbon–carbon and carbon–heteroatom bond forming reactions based on C–H activation. Target transformations are selected to enable 1) the use of simple and abundant starting materials such as aliphatic acids, amines and alcohols, and 2) disconnections that drastically shorten the synthesis of a drug molecule or a major class of biologically active compounds.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service