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914622

Sigma-Aldrich

Silica nanoparticles

pore size non-porous, 500 nm particle size, 5 % (w/w) in water, dispersion

Synonym(s):

Monodisperse silicon dioxide, Non-porous silica, Non-porous silicon dioxide, Silica

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About This Item

Empirical Formula (Hill Notation):
SiO2
CAS Number:
7631-86-9
Molecular Weight:
60.08
MDL number:
MFCD00011232
UNSPSC Code:
12352309
NACRES:
NA.23

form

dispersion
nanoparticles

Quality Level

100

concentration

5 % (w/w) in water

particle size

500 nm

pore size

non-porous

InChI

1S/O2Si/c1-3-2

InChI key

VYPSYNLAJGMNEJ-UHFFFAOYSA-N

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Application

Monodisperse nonporous silica nanoparticles find application in drug delivery and molecular imaging whereas micron sized particles are used in liquid chromatography. We offer highly monodisperse nonporous silica in aqueous solution, with sizes varying from 150 nm to 900 nm. The high monodispersity of our particles makes them suitable for aforementioned applications.

Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCN2178

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Zhigang Xu et al.
Nanoscale, 7(13), 5859-5868 (2015-03-12)
A myriad of drug delivery systems such as liposomes, micelles, polymers and inorganic nanoparticles (NPs) have been developed for cancer therapy. Very few of them, however, have the ability to integrate multiple functionalities such as specific delivery, high circulation stability
Li Tang et al.
Nano today, 8(3), 290-312 (2013-09-03)
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a large number
Martha Kim et al.
Scientific reports, 7(1), 8238-8238 (2017-08-16)
Nonporous silica nanoparticles (SiNPs) have potential as promising carriers for ophthalmic drugs. However, the in vivo safety of ocular topical SiNPs remains unclear. This study investigated the in vivo safety of oral and ocular topical applications of 100 nm-sized SiNPs in

Articles

Multidimensional Application of Nonporous Silica Nanoparticles

With the development of more monodispersed and size-controlled particles, nonporous SiNPs are now actively being investigated as promising nanocarrier systems for delivering drugs to various human tissues, and as novel materials for smart plastics

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