Skip to Content
Merck
All Photos(2)

Key Documents

More Documents

278785

Sigma-Aldrich

Triisobutylsilane

99%

Synonym(s):

Tris(2-methylpropyl)silane

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Linear Formula:
[(CH3)2CHCH2]3SiH
CAS Number:
6485-81-0
Molecular Weight:
200.44
Beilstein:
1738887
MDL number:
MFCD00010340
UNSPSC Code:
12352103
PubChem Substance ID:
24856831
NACRES:
NA.22

Quality Level

100

Assay

99%

refractive index

n20/D 1.435 (lit.)

bp

204-206 °C (lit.)

density

0.764 g/mL at 25 °C (lit.)

SMILES string

CC(C)C[SiH](CC(C)C)CC(C)C

InChI

1S/C12H28Si/c1-10(2)7-13(8-11(3)4)9-12(5)6/h10-13H,7-9H2,1-6H3

InChI key

BORQTRQJFUNMBC-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

Triisobutylsilane (TIBS) is a versatile organosilicon compound that finds several applications in organic synthesis. Some of its common applications include desulfurization, deprotection of the N-boc group, and radical reactions.

Application

Triisobutylsilane can be used as a reagent in combination with trifluoroacetic acid (TFA) for the deprotection of the Fmoc functional group.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

228.2 °F - closed cup

Flash Point(C)

109 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Thorsten Krause et al.
Frontiers in immunology, 11, 565243-565243 (2020-10-30)
Immunoglobulin E (IgE) is pivotal for manifestation and persistence of most immediate-type allergies and some asthma phenotypes. Consequently, IgE represents a crucial target for both, diagnostic purposes as well as therapeutic approaches. In fact, allergen-specific immunotherapy - aiming to re-route
Da Sun et al.
Bioconjugate chemistry, 30(3), 667-678 (2018-12-26)
CRISPR/Cas9 system is a promising approach for gene editing in gene therapy. Effective gene editing requires safe and efficient delivery of CRISPR/Cas9 system in target cells. Several new multifunctional pH-sensitive amino lipids were designed and synthesized with modification of the
Rongbing Yang et al.
Molecular pharmaceutics, 14(1), 252-263 (2017-01-04)
Desired characteristics of nanocarriers are crucial to explore its therapeutic potential. This investigation aimed to develop tunable bioresponsive newly synthesized unique arginine grafted poly(cystaminebis(acrylamide)-diaminohexane) [ABP] polymeric matrix based nanocarriers by using L9 Taguchi factorial design, desirability function, and multivariate method.
Thorsten Krause et al.
mAbs, 9(2), 333-341 (2016-12-03)
In chronic inflammatory airway diseases, mucins display disease-related alterations in quantity, composition and glycosylation. This opens the possibility to diagnose and monitor inflammatory airway disorders and their exacerbation based on mucin properties. For such an approach to be reasonably versatile

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service