158216

Methyl dichlorophosphate

85%

• Synonym(s): Methyl phosphorodichloridate
• Linear Formula: Cl₂P(O)OCH₃
• CAS Number: 677-24-7
• Molecular Weight: 148.91
• EC Number: 211-639-1
• MDL number: MFCD00002068
• UNSPSC Code: 12352100
• PubChem Substance ID: 24849724
• NACRES: NA.22

Properties

• Assay: 85%
• refractive index: n20/D 1.436 (lit.)
• bp: 62-64 °C/15 mmHg (lit.)
• density: 1.488 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: COP(Cl)(Cl)=O
• InChI: 1S/CH3Cl2O2P/c1-5-6(2,3)4/h1H3
• InChI key: SNVCRNWSNUUGEA-UHFFFAOYSA-N

Description

Application

Methyl dichlorophosphate was used in the synthesis of:

• 4,6-cyclic phosphate tetrasaccharide
• 8-(2′′-hydroxyethoxy)adenosine-5′,2′′-phosphate derivative
• analogs of (R)-1-O-hexadecyl-2-palmitoyl-sn-glycero-3-phosphoethanolamine poly(ethylene glycol)
• dioxaphosphorino[m,n-x]pyridines compounds

Analysis Note

may contain methyl alcohol as impurity

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves