14960
Bis(2-hydroxypropyl)amine
≥98.0% (T)
Synonym(s):
1,1′-Iminodi-2-propanol, Diisopropanolamine
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About This Item
Linear Formula:
NH[CH2CH(OH)CH3]2
CAS Number:
Molecular Weight:
133.19
Beilstein:
605363
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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![1-[N,N-Bis(2-hydroxyethyl)amino]-2-propanol 94%](/deepweb/assets/sigmaaldrich/product/structures/219/539/52108f19-e9a0-4987-b605-9969a5cc720d/640/52108f19-e9a0-4987-b605-9969a5cc720d.png)
Assay
≥98.0% (T)
form
solid
impurities
≤1% water
bp
249-250 °C/745 mmHg (lit.)
mp
42-45 °C (lit.)
solubility
H2O: miscible
alcohol: miscible
density
1.004 g/mL at 25 °C (lit.)
functional group
amine
SMILES string
CC(O)CNCC(C)O
InChI
1S/C6H15NO2/c1-5(8)3-7-4-6(2)9/h5-9H,3-4H2,1-2H3
InChI key
LVTYICIALWPMFW-UHFFFAOYSA-N
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Application
Bis(2-hydroxypropyl)amine (Diisopropanolamine) was used to study its effects upon choline uptake and phospholipid synthesis in Chinese hamster ovary (CHO) cells.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
275.0 °F - closed cup
Flash Point(C)
135 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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L M Gieg et al.
Canadian journal of microbiology, 45(5), 377-388 (1999-08-14)
Diisopropanolamine (DIPA) is a "sweetening agent" used to remove hydrogen sulfide from sour natural gas, and it is a contaminant at some sour gas treatment facilities in western Canada. To investigate the biodegradation of this alkanolamine, 14C-DIPA was used in
K Yamamoto et al.
Carcinogenesis, 10(9), 1607-1611 (1989-09-01)
The carcinogenic activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine (BHP) was investigated in male Wistar rats administered bis(2-hydroxypropyl)amine (BHPA) mixed in powder diet at a concentration of 1%, and sodium nitrite (SN) dissolved in distilled water at concentrations of 0.15 and 0.3%
Y Konishi et al.
IARC scientific publications, (105)(105), 318-321 (1991-01-01)
The carcinogenic activity of endogenously synthesized N-nitroso-bis(2-hydroxy-propyl)amine (NDHPA) was investigated in male Wistar rats administered bis(2-hydroxypropyl)amine (DHPA), mixed into a powdered diet at a concentration of 1%, and NaNO2 dissolved in distilled water at concentrations of 0.15% and 0.3%, for
K A Johnson et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(10), 1838-1845 (2007-05-18)
The repeated dose oral and dermal toxicity of diisopropanolamine (DIPA) was evaluated in rats and compared to the reported toxicity of the related secondary alcohol amine, diethanolamine (DEA). Fischer 344/DuCrl rats were given up to 750 mg/kg/day by dermal application
S A Saghir et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 45(10), 2047-2056 (2007-06-23)
This study was conducted to determine the relative dermal bioavailability (absorption), distribution, metabolism, and excretion (ADME) of diisopropanolamine (DIPA), an alcohol amine used in a number of industrial and personal care products. Groups of 4 female Fischer 344 rats received
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