- Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors.
Identification and Structure-Function Study of Positive Allosteric Modulators of Kainate Receptors.
Molecular pharmacology (2017-04-01)
Anja Probst Larsen, Sabine Fièvre, Karla Frydenvang, Pierre Francotte, Bernard Pirotte, Jette Sandholm Kastrup, Christophe Mulle
PMID28360094
ZUSAMMENFASSUNG
Kainate receptors (KARs) consist of a class of ionotropic glutamate receptors, which exert diverse pre- and postsynaptic functions through complex signaling regulating the activity of neural circuits. Whereas numerous small-molecule positive allosteric modulators of the ligand-binding domain of (
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