B352-05

Bovine Pulmonary Artery Smooth Muscle Cells: BPASMC (Cryovial)

• UNSPSC-Code: 41106514
• NACRES: NA.81

Eigenschaften

• Biologische Quelle: bovine pulmonary artery (tunica intima and media)
• Verpackung: pkg of 500,000 cells
• Hersteller/Markenname: Cell Applications, Inc
• Wachstumsmodus: Adherent
• Karyotyp: 2n = 60
• Morphologie: smooth muscle
• Methode(n): cell culture | mammalian: suitable
• Relevante Krankheit(en): cardiovascular diseases
• Versandbedingung: dry ice
• Lagertemp.: −196°C

Beschreibung

Allgemeine Beschreibung

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

BPASMC have been used in studies relevant to pulmonary hypertension characterized by hyperproliferation of pulmonary artery smooth muscle cells, the process shown to be mediated by hypoxia-induced expression of Bcl-xl (Suzuki, 2007). Additionally, they were used to elucidate the PKC-α dependent mechanisms of proMMP-2 activation and other signaling events in smooth muscle cells under pro-inflammatory conditions related to cell growth (Chakraborti, 2009; Roy, 2011, 2013; Dey, 2012; Chowdhury, 2013; Shaikh, 2013).

Characterization: positive for smooth muscle cell specific alpha-actin expression.

Ursprung der Zelllinie

Artery

Anwendung

cell growth, signaling, receptor transactivation and suppression, vascular remodeling

Komponenten

Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO

Angaben zur Herstellung

• 2nd passage, >500,000 cells in Bovine Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Subkultur-Routine

Please refer to the BPASMC Culture Protocol.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable