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F-903

Supelco

Fluphenazine dihydrochloride solution

1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

Empirische Formel (Hill-System):
C22H26N3OSF3 · H2Cl2
CAS-Nummer:
146-56-5
Molekulargewicht:
510.44
MDL-Nummer:
MFCD00055212
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329799780
NACRES:
NA.24

Qualität

certified reference material

Qualitätsniveau

300

Form

liquid

Leistungsmerkmale

Snap-N-Spike®/Snap-N-Shoot®

Verpackung

ampule of 1 mL

Hersteller/Markenname

Cerilliant®

Konzentration

1.0 mg/mL in methanol (as free base)

Methode(n)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Anwendung(en)

clinical testing

Format

single component solution

Lagertemp.

−20°C

InChI

1S/C22H26F3N3OS.2ClH/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29;;/h1-2,4-7,16,29H,3,8-15H2;2*1H

InChIKey

MBHNWCYEGXQEIT-UHFFFAOYSA-N

Angaben zum Gen

human ... DRD2(1813)

Verwandte Kategorien

Allgemeine Beschreibung

Fluphenazine, sold under the trade name Prolixin®, is a typical antipsychotic prescribed for treatment of schizophrenia, mania, bipolar disorder and dementia. This certified solution standard is suitable for fluphenazine testing methods by GC/MS or LC/MS for clinical toxicology, forensic analysis, or urine drug testing applications.

Anwendung


  • Monitoring Fluphenazine Metabolites in Schizophrenia: A study developed a radioimmunoassay for the 7-hydroxy metabolite of fluphenazine, applied to monitor plasma levels in patients treated long-term with oral and depot fluphenazine. This research enhances understanding of fluphenazine′s pharmacokinetics and aids in optimizing treatment regimens for schizophrenia, contributing to personalized medicine approaches (Aravagiri et al., 1994).

  • Neuroleptics in Clinical Practice: A review discusses the development and application of assays for neuroleptics, including fluphenazine, providing clinical perspectives on their use. This research is vital for enhancing therapeutic strategies and understanding the pharmacological profiles of antipsychotic drugs, which are crucial in treating severe mental disorders (Midha et al., 1993).

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Prolixin is a registered trademark of E.R. Squibb & Sons, LLC
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Gefahreneinstufungen

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

49.5 °F - closed cup

Flammpunkt (°C)

9.7 °C - closed cup

Zulassungslistungen

Zulassungslistungen werden hauptsächlich für chemische Produkte erstellt. Für nicht-chemische Produkte können hier nur begrenzte Angaben gemacht werden. Kein Eintrag bedeutet, dass keine der Komponenten gelistet ist. Es liegt in der Verantwortung des Benutzers, die sichere und legale Verwendung des Produkts zu gewährleisten.

EU REACH Annex XVII (Restriction List)

CAS No.

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Alcindo Busanello et al.
Pharmacology, biochemistry, and behavior, 101(2), 307-310 (2012-01-24)
Treatment with classical neuroleptics in humans can produce a serious side effect, known as tardive dyskinesia (TD). Here, we examined the possible neuroprotective effects of resveratrol, a polyphenol compound contained in red grapes and red wine, in an animal model
Yu-Wen Chen et al.
European journal of pharmacology, 693(1-3), 31-36 (2012-08-29)
The aim of this study was to examine whether thioxanthine-type antipsychotics (chlorprothixene and cis(z)-flupenthixol) and phenothiazine-type antipsychotics (chlorpromazine and fluphenazine) produced spinal anesthesia. Using a rat model of intrathecal injection, we evaluated spinal anesthesia of antipsychotic drugs (chlorprothixene, cis(z)-flupenthixol, chlorpromazine
David G Goodwin et al.
The Journal of parasitology, 97(1), 148-151 (2011-02-26)
An increasing interest in the association of the presence of antibodies to Toxoplasma gondii and the development of schizophrenia in patients has been generated over the last several years. Some antischizophrenia agents have been shown to have activity against T.
Irena Popović et al.
Psychiatria Danubina, 23(4), 384-388 (2011-11-15)
Schizophrenia is a severe chronic psychiatric disorder for which treatment compliance is important in the prevention of relapse. Second generation antipsychotics (SGA), such as Risperidone, have been found to be more effective in the treatment of such patients than the
Antipsychotic medication for early-episode schizophrenia.
John R Bola et al.
Schizophrenia bulletin, 38(1), 23-25 (2011-11-26)
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