850539P

Facade^™-EPC

3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane, powder

• Synonym(e): FA-7
• Empirische Formel (Hill-System): C₃₈H₇₄N₂O₁₁P₂
• CAS-Nummer: 1429405-99-1
• Molekulargewicht: 796.95
• UNSPSC-Code: 12352211
• NACRES: NA.25

Eigenschaften

• Assay: >99% (TLC)
• Form: powder
• Mol-Gew.: 796.95 g/mol
• Verpackung: pkg of 1 × 25 mg (850539P-25mg)
• Hersteller/Markenname: Avanti Research^™ - A Croda Brand 850539P
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])C[C@H]2OCCOP(OCC[N+](C)(C)C)([O-])=O)([H])C[C@H](OCCOP(OCC[N+](C)(C)C)([O-])=O)[C@@]4(C)[C@@]1([H])CC[C@@H]4[C@H](C)CCC
• InChI: 1S/C38H74N2O11P2/c1-11-12-28(2)31-13-14-32-36-33(27-35(38(31,32)4)47-22-24-51-53(44,45)49-20-18-40(8,9)10)37(3)16-15-30(41)25-29(37)26-34(36)46-21-23-50-52(42,43)48-19-17-39(5,6)7/h28-36,41H,11-27H2,1-10H3/t28-,29+,30-,31-,32+,33+,34-,35+,36+,37+,38-/m1/s
• InChIKey: RTNFJBQUBTXGHR-HECRFRQFSA-N

Beschreibung

Anwendung

Facade^™-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments. It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.

Biochem./physiol. Wirkung

Facade^™ EPC/FA-7 (3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.

Facade^™ is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.

Verpackung

5 mL Amber Glass Screw Cap Vial (850539P-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Facade is a trademark of Avanti Polar Lipids, LLC

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids